{"id":1372,"date":"2026-09-06T11:42:40","date_gmt":"2026-09-06T11:42:40","guid":{"rendered":"https:\/\/nex-chems.com\/?post_type=product&p=1372"},"modified":"2026-09-06T11:42:40","modified_gmt":"2026-09-06T11:42:40","slug":"lgd-4033-powder-ligandrol","status":"publish","type":"product","link":"https:\/\/nex-chems.com\/es\/product\/lgd-4033-powder-ligandrol\/","title":{"rendered":"LGD-4033 Powder (Ligandrol)"},"content":{"rendered":"

A. Introduction<\/h3>\n

LGD-4033 (Ligandrol)<\/b>\u00a0is one of the most extensively documented compounds in the SARM category. Developed to address muscle wasting and osteoporosis, it is utilized by research institutions to study the selective activation of androgen receptors in bone and muscle tissues with significantly reduced impact on the prostate and sebaceous glands compared to traditional androgens.<\/p>\n

B. Scientific Overview<\/h3>\n

Chemically identified as 4-((R)-2-((R)-2,2,2-trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-(trifluoromethyl)benzonitrile (C14\u200bH12\u200bF6\u200bN2\u200bO), LGD-4033 is a pyrrolidine-based ligand. In research settings, it is utilized to study the molecular mechanisms of myogenic differentiation and the up-regulation of anabolic gene expression. Its high binding affinity (Ki\u200b of ~1 nM) makes it an essential reference standard for comparative pharmacological analysis.<\/p>\n

C. Product Specifications<\/h3>\n
    \n
  • Form:<\/b>\u00a0Crystalline powder<\/li>\n
  • Chemical Class:<\/b>\u00a0Pyrrolidine \/ SARM<\/li>\n
  • Molecular Formula:<\/b>\u00a0C14\u200bH12\u200bF6\u200bN2\u200bO<\/li>\n
  • Molecular Weight:<\/b>\u00a0338.25 g\/mol<\/li>\n
  • Purity:<\/b>\u00a0\u226599% (HPLC\/NMR Verified)<\/li>\n
  • Solubility:<\/b>\u00a0Soluble in DMSO (up to 30 mg\/mL) and Ethanol<\/li>\n
  • Storage:<\/b>\u00a0Store at room temperature (15\u00b0C to 25\u00b0C) in a dry, airtight container protected from light and moisture.<\/li>\n<\/ul>\n

    D. Laboratory Use Context<\/h3>\n

    LGD-4033 powder is provided exclusively for\u00a0in-vitro research<\/b>\u00a0and\u00a0analytical testing<\/b>. It is a primary reagent for:<\/p>\n

      \n
    • Investigating tissue-selective androgen receptor modulation in cell cultures.<\/li>\n
    • Studying the molecular pathways of osteoblast activity and muscle protein synthesis.<\/li>\n
    • Calibration and validation of LC-MS and GC-MS equipment for SARM screening.<\/li>\n
    • In-vitro<\/i>\u00a0toxicity and stability profiling in synthetic biological matrices.<\/li>\n<\/ul>\n

      E. Quality Testing<\/h3>\n
        \n
      • HPLC Verification:<\/b>\u00a0Every batch is rigorously tested to confirm \u226599% chemical purity and the absence of related synthesis precursors.<\/li>\n
      • Structural Identity:<\/b>\u00a0Mass Spectrometry (MS) and Proton NMR verify the presence of the trifluoromethyl and pyrrolidine structural components.<\/li>\n
      • Batch Consistency:<\/b>\u00a0Manufactured under strict laboratory protocols to ensure reproducible results for complex longitudinal studies.<\/li>\n
      • COA:<\/b>\u00a0Comprehensive Certificates of Analysis are available for all institutional research requirements.<\/li>\n<\/ul>\n

        F. Shipping Handling<\/h3>\n

        Our LGD-4033 powder is dispatched in professional, moisture-proof, and UV-protected packaging to maintain chemical integrity during transit. We provide reliable, discreet worldwide shipping to support the requirements of international research facilities and commercial laboratories.<\/p>\n

        G. Compliance Disclaimer (CLEAR PROMINENT)<\/h3>\n

        FOR RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION.<\/b>\u00a0This product is a research chemical and is strictly intended for\u00a0in-vitro<\/i>\u00a0laboratory applications and analytical testing. It is not intended for diagnostic or therapeutic use in humans or animals. No medical instructions or dosages are provided. The purchaser is solely responsible for compliance with all local and international laws regarding the acquisition and handling of this substance.<\/p><\/blockquote>","protected":false},"excerpt":{"rendered":"

        A. Introduction LGD-4033 (Ligandrol)\u00a0is one of the most extensively documented compounds in the SARM category. Developed to address muscle wasting […]<\/p>\n","protected":false},"featured_media":1373,"comment_status":"open","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[262,261],"product_tag":[],"class_list":["post-1372","product","type-product","status-publish","has-post-thumbnail","product_cat-sarms","product_cat-muscle-growth-bulking","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","shipping-taxable","purchasable","product-type-simple"],"uagb_featured_image_src":{"full":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/LGD-4033-Powder-Ligandrol.jpg",500,500,false],"thumbnail":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/LGD-4033-Powder-Ligandrol-150x150.jpg",150,150,true],"medium":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/LGD-4033-Powder-Ligandrol-300x300.jpg",300,300,true],"medium_large":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/LGD-4033-Powder-Ligandrol.jpg",500,500,false],"large":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/LGD-4033-Powder-Ligandrol.jpg",500,500,false],"1536x1536":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/LGD-4033-Powder-Ligandrol.jpg",500,500,false],"2048x2048":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/LGD-4033-Powder-Ligandrol.jpg",500,500,false],"trp-custom-language-flag":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/LGD-4033-Powder-Ligandrol-12x12.jpg",12,12,true],"woocommerce_thumbnail":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/LGD-4033-Powder-Ligandrol-300x300.jpg",300,300,true],"woocommerce_single":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/LGD-4033-Powder-Ligandrol.jpg",500,500,false],"woocommerce_gallery_thumbnail":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/LGD-4033-Powder-Ligandrol-100x100.jpg",100,100,true]},"uagb_author_info":{"display_name":"admin","author_link":"https:\/\/nex-chems.com\/es\/author\/"},"uagb_comment_info":0,"uagb_excerpt":"A. Introduction LGD-4033 (Ligandrol)\u00a0is one of the most extensively documented compounds in the SARM category. Developed to address muscle wasting […]","_links":{"self":[{"href":"https:\/\/nex-chems.com\/es\/wp-json\/wp\/v2\/product\/1372","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nex-chems.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nex-chems.com\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nex-chems.com\/es\/wp-json\/wp\/v2\/comments?post=1372"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nex-chems.com\/es\/wp-json\/wp\/v2\/media\/1373"}],"wp:attachment":[{"href":"https:\/\/nex-chems.com\/es\/wp-json\/wp\/v2\/media?parent=1372"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nex-chems.com\/es\/wp-json\/wp\/v2\/product_brand?post=1372"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nex-chems.com\/es\/wp-json\/wp\/v2\/product_cat?post=1372"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nex-chems.com\/es\/wp-json\/wp\/v2\/product_tag?post=1372"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}