{"id":1314,"date":"2026-09-05T22:16:01","date_gmt":"2026-09-05T22:16:01","guid":{"rendered":"https:\/\/nex-chems.com\/?post_type=product&p=1314"},"modified":"2026-09-05T22:16:01","modified_gmt":"2026-09-05T22:16:01","slug":"gw-0742-powder","status":"publish","type":"product","link":"https:\/\/nex-chems.com\/fr\/product\/gw-0742-powder\/","title":{"rendered":"GW-0742 Powder"},"content":{"rendered":"

A. Introduction<\/h3>\n

GW-0742<\/b>\u00a0is an essential research tool used to investigate the physiological roles of the PPAR\u03b4 isoform. Due to its high potency and selectivity (1000-fold over other PPAR subtypes), it is a preferred ligand for laboratories exploring the regulation of fatty acid metabolism, inflammation, and energy homeostasis in various tissue models.<\/p>\n

B. Scientific Overview<\/h3>\n

Chemically identified as [4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]acetic acid ($C_{21}H_{17}F_{4}NO_{3}S_{2}$), GW-0742 differs from GW-501516 by the addition of a fluorine atom at the 3-position of the phenyl ring. In research settings, it is utilized to activate the PPAR\u03b4-mediated transcriptional program, which oversees the expression of proteins involved in mitochondrial biogenesis and cholesterol transport.<\/p>\n

C. Product Specifications<\/h3>\n
    \n
  • Form:<\/b>\u00a0Crystalline powder<\/li>\n
  • Chemical Class:<\/b>\u00a0PPAR\u03b2\/\u03b4 Agonist \/ Thiazole derivative<\/li>\n
  • Molecular Formula:<\/b>\u00a0$C_{21}H_{17}F_{4}NO_{3}S_{2}$<\/li>\n
  • Molecular Weight:<\/b>\u00a0471.5 g\/mol<\/li>\n
  • Purity:<\/b>\u00a0\u226599% (HPLC\/NMR Verified)<\/li>\n
  • Solubility:<\/b>\u00a0Soluble in DMSO (up to 25 mg\/mL) and Ethanol<\/li>\n
  • Storage:<\/b>\u00a0Store at room temperature (15\u00b0C to 25\u00b0C) in a dry, airtight container protected from light.<\/li>\n<\/ul>\n

    D. Laboratory Use Context<\/h3>\n

    GW-0742 powder is provided exclusively for\u00a0in-vitro research<\/b>\u00a0and\u00a0analytical testing<\/b>. It is an ideal reagent for:<\/p>\n

      \n
    • Investigating PPAR\u03b4-dependent gene expression in cardiac and skeletal muscle cultures.<\/li>\n
    • Studying the molecular pathways of glucose utilization and lipid oxidation.<\/li>\n
    • Calibration and validation of LC-MS and GC-MS equipment.<\/li>\n
    • Comparative structural analysis between halogenated PPAR ligands.<\/li>\n<\/ul>\n

      E. Quality Testing<\/h3>\n
        \n
      • HPLC Verification:<\/b>\u00a0Every batch is rigorously tested to confirm high chemical purity and exact molecular composition.<\/li>\n
      • Structural Identity:<\/b>\u00a0Mass Spectrometry (MS) and Proton NMR verify the presence of the trifluoromethyl-fluorophenyl-thiazole structure.<\/li>\n
      • Batch Consistency:<\/b>\u00a0Manufactured under strict protocols to ensure reproducible results for complex longitudinal studies.<\/li>\n
      • COA:<\/b>\u00a0Comprehensive Certificates of Analysis are provided for all institutional research requirements.<\/li>\n<\/ul>\n

        F. Shipping Handling<\/h3>\n

        Our GW-0742 powder is dispatched in professional, moisture-proof, and UV-protected packaging to maintain chemical integrity during transit. We offer reliable, discreet worldwide shipping to support the requirements of international research facilities and commercial laboratories.<\/p>\n

        G. Compliance Disclaimer (CLEAR PROMINENT)<\/h3>\n

        FOR RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION.<\/b>\u00a0This product is a research chemical and is strictly intended for\u00a0in-vitro<\/i>\u00a0laboratory applications and analytical testing. It is not intended for diagnostic or therapeutic use in humans or animals. No medical instructions or dosages are provided. The purchaser is solely responsible for compliance with all local and international laws regarding the acquisition and handling of this substance.<\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"

        A. Introduction GW-0742\u00a0is an essential research tool used to investigate the physiological roles of the PPAR\u03b4 isoform. Due to its […]<\/p>\n","protected":false},"featured_media":1315,"comment_status":"open","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[258,259,260,261,262],"product_tag":[],"class_list":["post-1314","product","type-product","status-publish","has-post-thumbnail","product_cat-endurance","product_cat-fat-loss-cutting","product_cat-gw-0742","product_cat-muscle-growth-bulking","product_cat-sarms","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","shipping-taxable","purchasable","product-type-simple"],"uagb_featured_image_src":{"full":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/GW-0742-Powder.png",500,500,false],"thumbnail":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/GW-0742-Powder-150x150.png",150,150,true],"medium":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/GW-0742-Powder-300x300.png",300,300,true],"medium_large":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/GW-0742-Powder.png",500,500,false],"large":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/GW-0742-Powder.png",500,500,false],"1536x1536":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/GW-0742-Powder.png",500,500,false],"2048x2048":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/GW-0742-Powder.png",500,500,false],"trp-custom-language-flag":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/GW-0742-Powder-12x12.png",12,12,true],"woocommerce_thumbnail":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/GW-0742-Powder-300x300.png",300,300,true],"woocommerce_single":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/GW-0742-Powder.png",500,500,false],"woocommerce_gallery_thumbnail":["https:\/\/nex-chems.com\/wp-content\/uploads\/2026\/09\/GW-0742-Powder-100x100.png",100,100,true]},"uagb_author_info":{"display_name":"admin","author_link":"https:\/\/nex-chems.com\/fr\/author\/"},"uagb_comment_info":0,"uagb_excerpt":"A. Introduction GW-0742\u00a0is an essential research tool used to investigate the physiological roles of the PPAR\u03b4 isoform. Due to its […]","_links":{"self":[{"href":"https:\/\/nex-chems.com\/fr\/wp-json\/wp\/v2\/product\/1314","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nex-chems.com\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/nex-chems.com\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/nex-chems.com\/fr\/wp-json\/wp\/v2\/comments?post=1314"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nex-chems.com\/fr\/wp-json\/wp\/v2\/media\/1315"}],"wp:attachment":[{"href":"https:\/\/nex-chems.com\/fr\/wp-json\/wp\/v2\/media?parent=1314"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/nex-chems.com\/fr\/wp-json\/wp\/v2\/product_brand?post=1314"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/nex-chems.com\/fr\/wp-json\/wp\/v2\/product_cat?post=1314"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/nex-chems.com\/fr\/wp-json\/wp\/v2\/product_tag?post=1314"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}